| Chineses Pinyin | ShengJiang | ||
| Use Part | Fresh rhizome | ||
| Habitat | SiChuan, GuiZhou, HuBei, GuangDong, GuangXi | ||
| Flavor | Pungent | ||
| Meridian Tropism | Lung; Spleen; Stomach | ||
| Species |
>Kingdom: Viridiplantae
-->Phylum: Streptophyta
-->Class: Equisetopsida
-->Order: Zingiberales
-->Family: Zingiberaceae
-->Genus: Zingiber
-->Species: Zingiber officinale
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| Pair Name | Ginger extract, Doxorubicin | |||
| Partner Name | Doxorubicin | |||
| Disease Info | [ICD-11: 2A00-2F9Z] | Solid tumour or cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Down-regulation | Expression | CCND1 | hsa595 |
| Down-regulation | Expression | NFKB1 | hsa4790 | |
| Up-regulation | Phosphorylation | PRKAA1 | hsa5562 | |
| Up-regulation | Expression | TP53 | hsa7157 | |
| In Vivo Model | 1×10⁶ EAC cells were implanted subcutaneously into the right thigh of the lower limb of mice. | |||
| Result | AMPK pathway and cyclin D1 gene expression could be a molecular therapeutic target for the anticancer effect of GE in mice bearing SEC. Combining GE and DOX revealed a greater efficacy as anticancer therapeutic regimen. | |||
